Huelgas willing to represent PH ‘in a heartbeat’ in 2019 SEA Games

first_imgPencak Silat: PH finishes 6th in men’s doubles OSG plea to revoke ABS-CBN franchise ‘a duplicitous move’ – Lacson “It will be an honor to represent the country on your home soil, but I take it race by race. As they say, you get more injury prone when you get older,” he said.Sports Related Videospowered by AdSparcRead Next View comments Trending Articles PLAY LIST 00:50Trending Articles02:11SEA GAMES 2019: PH’s Nesthy Petecio boxing featherweight final (HIGHLIGHTS)08:07Athletes treated to a spectacle as SEA Games 2019 officially ends06:27SEA Games 2019: No surprises as Gilas Pilipinas cruises to basketball gold05:02SEA Games 2019: Philippines clinches historic gold in women’s basketball05:21Drama in karate: Tsukii ‘very sad’ over coach’s bullying, cold shoulder03:24PH’s James Palicte boxing light welterweight final (HIGHLIGHTS) MOST READ Britain’s Prince Harry and Meghan Markle to give up royal titles Filipino triathlete Nikko Huelgas shows off his second straight SEA Games gold medal. Mark Giongco/INQUIRER.netThere’s no way Nikko Huelgas, who has risen as the face of Philippine triathlon, is going to pass up on a chance to represent the country in the next edition of the Southeast Asian Games two years from now.Especially when the next staging of regional sports spectacle will be in the country.ADVERTISEMENT National Historical team rescues Amorsolos, artifacts from Taal Don’t miss out on the latest news and information. center_img “Definitely, I want to compete again. I’d do it in a heartbeat,” Huelgas told INQUIRER.net during his hero’s welcome dinner at Discovery Suites Hotel Wednesday night.Huelgas successfully defended his men’s triathlon crown in the SEA Games on Sunday after the Philippines finished 1-2 in the event with John Chicano claiming silver.FEATURED STORIESSPORTSEnd of his agony? SC rules in favor of Espinosa, orders promoter heirs to pay boxing legendSPORTSRedemption is sweet for Ginebra, Scottie ThompsonSPORTSMayweather beats Pacquiao, Canelo for ‘Fighter of the Decade’Huelgas’ eyes lit up when asked about the possibility of going for a third consecutive SEA Games gold medal in front of his countrymen, but he also doesn’t want to look to far ahead.The 26-year-old Huelgas is set to go back to training sooner than later and though his best years are still ahead of him, he is wary of the wear and tear that every athlete who undergoes rigorous training is susceptible to. Hotdog’s Dennis Garcia dies Bishop Baylon encourages faithful in Albay to help Taal evacuees LATEST STORIES What’s in store for your animal sign this year Police seize P68-M worth of ‘shabu’ in Pasay Marcosian mode: Duterte threatens to arrest water execs ‘one night’ Search on for 5 Indonesians snatched anew in Lahad Datulast_img read more

Pathogens Don’t Exist

first_img(Visited 364 times, 1 visits today)FacebookTwitterPinterestSave分享0 It takes a partnership to have a disease, say two microbiologists who argue for ditching the word “pathogen.”Pathogens – disease germs – seem so real, it looks really cranky to claim they don’t exist.  Isn’t the Ebola virus a terrible pathogen that doctors are fighting in Africa?  But listen to Casadevall and Pirofsky in Nature today:The term pathogen started to be used in the late 1880s to mean a microbe that can cause disease. Ever since, scientists have been searching for properties in bacteria, fungi, viruses and parasites that account for their ability to make us ill. Some seminal discoveries have resulted — such as the roles of various bacterial and fungal toxins in disease. Indeed, our oldest and most reliable vaccines, such as those for diphtheria and tetanus, work by prompting the body to produce antibodies that neutralize bacterial toxins.Yet a microbe cannot cause disease without a host. What actually kills people with diphtheria, for example, is the strong inflammatory response that the diphtheria toxin triggers, including a thick grey coating on the throat that can obstruct breathing. Likewise, it is the massive activation of white blood cells triggered by certain strains of Staphylococcus and Streptococcus bacteria that can lead to toxic-shock syndrome.Disease is one of several possible outcomes of an interaction between a host and a microbe. It sounds obvious spelled out in this way. But the issue here is more than just semantics: the use of the term pathogen sustains an unhelpful focus among researchers and clinicians on microbes that could be hindering the discovery of treatments.Imagine a staph germ just sitting there in the environment.  It’s not hurting anyone.  It might even have a beneficial function.  It’s your fault.  It’s your darn body that gets carried away in an overreaction, they seem to be saying.  That is certainly a novel way to think about disease germs!Could we find treatments easier by changing our focus from the evil germ to the uncooperative interactions of innocent cells with our bodies?  “Context is everything,” Casadevall and Pirofsky argue, providing several examples of how the same microbe can cause different effects in different people.  There are clear-cut cases of knocking out the “virulence factors” in tetanus and diphtheria, but success against pneumonia-causing agents has been difficult.Work on vaccines has provided further indications of there being flaws in the idea that discrete factors, akin to toxins, enable all microbes to cause disease.  What is more, many of the ongoing attempts to develop new vaccines by identifying and targeting virulence factors have so far proved fruitless.  Despite decades of searching, no classical virulence factor suitable for vaccine development has been identified for the tuberculosis bacillus or malaria parasite.What do they suggest?  They acknowledge that getting “pathogen” out of the dictionary is not going to happen, but we should recognize the metaphor’s limitations.  It’s a “reductionist” approach, they say, to treat the host as a constant and the microbe as a variable.  Instead, researchers need to focus more on the host-microbe interaction:New tools are needed to measure the spectrum of inflammatory, biochemical and other forms of damage resulting from the interaction between hosts and microbes. The discovery and development of these tools must be driven by new sessions at conferences, special issues of journals and dedicated funding streams. We think that such a shift in approach would uncover all sorts of possibilities for preventing infectious diseases.Related Health IssuesToxin sharing:  A related article in Science Daily talks about “virulence agents” like “microbe toxin genes,” in Lyme disease bacteria, but then shares the surprising news that “Microbe toxin genes have jumped to ticks, mites and other animals.”  There seems to be some kind of arms-trade agreement going on. We’re all familiar with the picture of the evil germ injecting its poison into the host, but—Now, in a surprising twist, Mougous and colleagues [U of Washington] have found that many animals have taken a page from the bacterial playbook. They steal these toxins to fight unwanted microbes growing in or on them. The researchers describe their findings in a report to be published online Nov. 24 in the journal Nature.This finding opens the possibility that the enemy of my enemy is my friend, in the internal battle for homeostasis.  By horizontal gene transfer, animals can hack the software bacteria use to fight their own enemies.  But then, is warfare a proper metaphor at all?How the toxins function in organisms other than ticks remains to be explored. The researchers now are looking at the possibility that other bacterial toxins have been repurposed by animals for antibacterial defense.Toxic fruit:  PhysOrg has a story about fruit flies that have adapted to the toxic fruit of a certain tree.  All other species of fruit flies are killed by it, but this one species is not repulsed by the odor.  “The flies are strongly attracted by the fruits of the morinda tree: they feed on its fruits, and females prefer to lay their eggs on these.”  What’s poison to one is food to another.Snake venom:  Snakebite: now there’s a really scary situation for humans.  Once inside the body, those toxins can wreak havoc on nerves, muscles and tissues, and even cause death.  But take a look at the “new model of snake venom evolution proposed” in Science Daily.  Maybe the snake wasn’t nefariously plotting to cause us pain.Researchers [at U of Texas] have found genetic evidence that highly toxic venom proteins were evolutionarily ‘born’ from non-toxic genes, which have other ordinary jobs around the body, such as regulation of cellular functions or digestion of food.The researchers are identifying the functions of these toxins “before they evolved into toxins.”  Obviously they are not toxic to the snake, who manufactures and stores them.  Are snakes just repurposing their original household tools for later needs, like hunting and defense?Castoe said that with an uptick in genetic analysis capabilities, scientists are finding more evidence for a long-held theory. That theory says highly toxic venom proteins were evolutionarily “born” from non-toxic genes, which have other ordinary jobs around the body, such as regulation of cellular functions or digestion of food.“These results demonstrate that genes or transcripts which were previously interpreted as ‘toxin genes’ are instead most likely housekeeping genes, involved in the more mundane maintenance of normal metabolism of many tissues,” said Stephen Mackessy, a co-author on the study and biology professor at the University of Northern Colorado. “Our results also suggest that instead of a single ancient origin, venom and venom-delivery systems most likely evolved independently in several distinct lineages of reptiles.”This thinking meshes a little with the ideas from Casadevall and Pirofsky: it’s misleading to consider snake venom a “pathogen” of sorts.  We must focus on the interaction of the substance within the host body.   Those genes would tend to become more expressed at higher levels—up to a point:Based on their data, the new paper presents a model with three steps for venom evolution. First, these potentially venomous genes end up in the oral gland by default, because they are expressed in low but consistent ways throughout the body. Then, because of natural selection on this expression in the oral gland being beneficial, tissues in the mouth begin expressing those genes in higher levels than in other parts of the body. Finally, as the venom evolves to become more toxic, the expression of those genes in other organs is decreased to limit potentially harmful effects of secreting such toxins in other body tissues.This is not Darwinian natural selection; it’s just adjustment of existing genetic information (how much it is expressed, and in what tissues).  The snakes don’t want to shoot themselves in the foot!  (Note: snakes do not have feet.)  Snakes are not evil sinners, but some evolutionary models are:The team calls its new model the Stepwise Intermediate Nearly Neutral Evolutionary Recruitment, or SINNER, model. They say differing venom levels in snakes and other animals could be traced to the variability of where different species, or different genes within a species, are along the continuum between the beginning and end of the SINNER model….“What is a venom and what species are venomous will take a lot more evidence to convince people now,” Castoe said. “It provides a brand new perspective on what we should think of when we look at those oral glands.”What all these stories have in common is the repurposing of existing genetic information as interactions between organisms are explored in various environments.We offer these news items to creation ecologists who would like to consider possible avenues for the origin of “natural evil.”  The Curse as described in Genesis 3 may not have involved creation of harmful agents de novo.  Instead, it may have involved minor adjustments to existing structures, or relaxation of controls on the maintenance of structures, or relaxation of controls on interactions between organisms.  Instead of a controlled, harmonious ecosystem, it became a more chaotic ecology, with organisms getting by as best they could, within certain constraints (God’s continuing care for His creation).  Anyway, these are new and interesting ways to think about the issues.last_img read more

South Africa to pilot smart ID cards

first_img8 May 2012 South Africans will move one step closer to having smart card IDs when the Department of Home Affairs launches the pilot of its smart ID project, which promises to speed up government services while cutting down on crime and corruption involving identity documents. Briefing journalists in Pretoria last week, Home Affairs Director-General Mkuseli Apleni said the pilot – to be launched within the next six months – would involve the issue of 2 000 smart IDs to allow for the testing of the smart cards’ systems, hardware and software. “It will also enable the government to procure the required machinery to produce the volume of cards that will be required, so that we eventually completely phase out the current green bar-coded ID.”Old IDs to be phased out over four years Home Affairs Minister Nkosazana Dlamini-Zuma said last month that the roll-out of the smart IDs – their issue to new ID applicants – would begin in 2013. Apleni said that, once all the systems were tested and in place to produce the smart cards, all new ID applications would be treated as applications for smart IDs – at which point the minister would promulgate the costs of the smart IDs for citizens. These are expected to be similar to the current costs for documents. It was possible that the green bar-coded ID could eventually be phased out over about four years, Apleni said.One card fits all? Apleni said the government was looking at having South Africans use just one card for all their official documentation requirements – identities, licences, National Health Insurance, social grants. He said the departments of transport, health and social development were wanting to be involved in the project, adding that Home Affairs would look into how it could upscale the chip on the cards in order to accommodate these departments. BuaNews and SAinfo reporterlast_img read more

The Célinaissance How Celine Dion became cool

first_imgIn today’s Big Story podcast, Céline Dion has been many things throughout her career, but “cool” has rarely been one of them. As one of the bestselling artists to call this country home, and an unabashedly proud Canadian and Quebecer, Céline should have won us all over long ago. But she never quite broke through to the more cynical younger generation.Until that generation stopped being cynical, that is. It turns out Céline Dion was always cool. She was just waiting for us to come to her. And over the past few years, we have, by the millions.GUEST: Suzannah Showler, the WalrusYou can subscribe to The Big Story podcast on Apple Podcasts, Google and SpotifyYou can also find it at thebigstorypodcast.ca.last_img

Government Speaks and Warns About Ebola Virus

first_img Health: Mosquitoes are to be taken seriously TCI Health warns against Zika as Caribbean counts five cases Related Items:chickv, Chikungunya, Ebola Mosquitoes on the attack; residents run, one school closed up Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 06 Oct 2014 – Since launching our ChikV informational music video, set to the sounds of young Wayne J out of Jamaica seven days ago, Magnetic Media has seen nearly 84 thousand people watching it… meanwhile government is finally speaking and warning on the scary Ebola virus. Stakeholder meetings are being planned explained health officials in a release this morning… and while the health department is not restricting travel to Ebola cities or countries, be prepared to possibly be held for advanced screening as the Ministry called it; in fact you could be subjected to Ebola isolation for as many as 21 days as a part of TCI’s enhanced surveillance of this virus”. Add to this, if you have recently been to any of the countries or cities where Ebola is now cited, then you should go and see a doctor straight away. In the end, our health system says it is ready in a worst case scenario of an Ebola outbreak… saying we continue with stringent efforts to prepare to recognise, evaluate and manage any case of the Ebola virus, in the unlikely event a case occurs in the Territory. Recommended for youlast_img read more

NASSCO hiring up to 1000 workers to build Navy ships

first_img Posted: April 13, 2018 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsThey’ve been the hometown ship builder since 1944 when they cranked out the first “tuna boat” for the fishing industry. Fast forward 70-years and NASSCO is bigger than ever.“This is exciting. We have new Navy contracts and we’re hiring 800 to 1000-workers”, says Dennis Dubard of NASSCO. He also happens to be the former Commanding Officer of the U.S.S. Peleliu.“We’ve never had a contract like this in NASSCO history, with sustained work like this”, says DuBard. “It’s a very important program. We’re building refueling tankers for the Navy, for the aircraft carrier groups”.Since this is hometown company, their focus is hiring hometown people. “We have an arrangement with San Diego City College to train workers for the long term. “This is long term”, says DuBard.With the Navy contract and another “private” contract, there will be good paying jobs for at least the next 7-years, 2025. “At the end of the day, we can see the fruits of our labor. We can say, I’m a part of something bigger than myself. We can look at the finished product and say, I built that”, says DuBard.A pay check and a sense of pride. Now that’s the right stuff. Dan Plante Updated: 7:43 PM Categories: Local San Diego News FacebookTwittercenter_img Dan Plante, April 13, 2018 NASSCO hiring up to 1,000 workers to build Navy shipslast_img read more

New Technologies That May Save Lives

first_img Citation: New Technologies That May Save Lives (2007, October 19) retrieved 18 August 2019 from https://phys.org/news/2007-10-technologies.html Explore further The combined efforts of NEC and Tatung to implement WiMax will go on show next week at the WiMax Forum. This is part of the M-Taiwan project focused on providing mobile emergency services including transmission of x-ray, patient medical history, vitals while patients are en route to the hospital. WiMax is particularly suited for ambulances, according to NEC press releases.The efforts and contributions of NEC allowed WiMax to achieve 6 Mbps transmission per user. This is vital in exchanging large data sources such as patient records and x-rays. WiMax is a high speed broadband service that is particularly designed for use in vehicles traveling at excessive speeds. The WiMax will transmit vital information about the patient while en route to the hospital. This vital information allows emergency physicians to relay life saving instructions to the paramedic at the accident scene and in those vital minutes following a traumatic event. A NEC WiMax Research and Design Center will open by the end of 2007 in collaboration with the Taiwanese government. The Center will focus on creating an environment for vendors to utilize the end-to- end wireless platform and base station in the creation of new and life saving applications and technologies. The experimental trials of NEC and WiMax took place recently in the city of Hualien. It was a trial commissioned by the Taiwanese government to implement the M-Taiwan project. The city of Hualien plans to use the system for tourism and medical services. The preliminary test results indicate the system did very well in transmitting smoothly through base stations and in providing stability within the vehicle while traveling at high speeds. The new research and design center will enable other technologies to build on the work of NEC WiMax. NEC in a separate press release announced two new 21.3 inch amorphous silicon color thin film transistors , liquid crystal display modules ideal for medical applications. These two highly sophisticated displays are ideal for medical imaging diagnosis of patient illness or trauma. The product samples will be available in late November, 2007. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. NEC to Deliver First Mobile WiMAX Solutions to Worldwide Market New NEC LCD Medical Technology As part of the M-Taiwan project, NEC and Tatung will demonstrate life saving technologies at the WiMax Forum next week. The forum will display the efforts of NEC in providing ambulance to hospital large file transmissions without interruption. A NEC Research and Development Center will open by years end for future enhancements of the technologies. last_img read more