Drake sophomore Alyssa Brand (Skokie, Ill.) evened the score at 2-2 at the 50-minute mark (50:27) as Brand beat the ISU defense, fired a strike from deep on the far side of the field that found the back of the net for her team-leading fifth goal. “Tonight’s result is disheartening,” said head coach Lindsey Horner. “We got the ball into dangerous areas and were quite good for stretches of the game especially in the second half. We defended so well and to deflect two goals into our own net was too much for us to overcome this evening.” at Iowa State 10/18/2016 – 7 PM Illinois State took the lead back at the 57-minute mark (57:59) as Koehl scored again. Drake (9-4-2, 0-3-1 MVC) scored the match’s first goal as senior Kayla Armstrong (Cedar Rapids, Iowa) stole the ball from Illinois State’s (9-5-2, 3-0-1 MVC) defense. Armstrong fired a shot to the far post that found the back of the net to put the Bulldogs up 1-0. Her goal came in the 22nd minute (22:05) of the match and is the fourth of the year for the senior. PDF Box Score Drake visits Ames, Iowa, Oct. 18 for a non-conference match with the Iowa State Cyclones. First kick at the Cyclone Sports Complex is set for 7 p.m. The Bulldogs host their season-finale on Oct. 22 when they welcome Missouri State at 2 p.m. Print Friendly Version Cyclones TV In the final 10 minutes, senior Sarah Grace Nicholson (Overland Park, Kan.) headed a ball off a deep service ball that was just left of the net. Later junior Brooke Salisbury (Kearney, Mo.) blasted a shot that ISU’s goalie, Haley Smith had slip through her hands but go out of the goal box. Watch Live DES MOINES, Iowa – The Illinois State Redbirds rallied to defeat the Drake University women’s soccer team, 3-2, Saturday night in Missouri Valley Conference play at the Cownie Soccer Stadium. Live Stats Next Game: Illinois State answered with goals from Lauren Koehl (26:42) and Kelli Zickert (34:42) as the Redbirds led 2-1 at halftime. HTML Box Score Story Links Drake continued to be the aggressive team firing several more shots that were so close to finding the net. Full Schedule Roster “Credit Illinois State for putting the ball into dangerous areas,” Horner said. “It was great to see Kayla put the team on her back and be so dangerous with the ball. Alyssa’s goal was pure determination. At this point we have to continue to work for results and fight our way into the MVC tournament. There is a sense of fight about us and enough quality that we can grind out some results here to come.” Preview
The writing has been on the wall for months, and on Monday, Bruce Bochy read it: 2019 will be his last season as the Giants’ manager.Bochy’s announcement wasn’t surprising. That said, the timing and setting did catch more than a few off guard.But it’s telling that San Francisco’s greatest manager didn’t want some fussy press conference or a video montage tribute to mark his final campaign — he merely dropped a bombshell during his daily media availability in the Giants’ dugout at the team’s …
(Visited 16 times, 1 visits today)FacebookTwitterPinterestSave分享0 The structure of an important potassium-ion gate in the membrane of brain cells has been found to open like a camera iris.In Nature, Eitan Reuveny described a paper in the same issue by Whorton and MacKinnon that reveals how an important molecular gate named GIRK2 works in the membranes of brain cells. These gates control the passage of potassium ions (K+) to the outside of the cell, a process that changes the electrical charge between inside and outside, allowing conduction of electrical signals. His description, “Ion channel twists to open,” compares the twisting motion of the components to a camera iris: “The conformational changes that open the inner helical gate are comparable to the widening of a lens aperture by hand-rotating the aperture ring.”But whose hands rotate the ring? The cylindrical channel that allows passage of K+ ions is surrounded by four complex proteins that lock into the cell membrane. Activation of these “hands” by G-protein coupled receptors makes them turn the channel, opening it just a bit wider, but not enough, to allow the ions through. From there, random perturbations may permit the ions to “burst” through the narrow opening as observed in living cells. The channel also contains a “selectivity filter” to ensure only K+ ions can make it through.Reuveny began by explaining the importance of these channcels:Ion channels are the main units responsible for the electrical activity in our body. They constitute a large family of some 400 proteins in humans. A subfamily of these proteins consists of four GIRK channels, which specialize in converting chemical signals — mostly those of neurotransmitter molecules such as acetylcholine, dopamine, serotonin and adrenaline — into electrical ones in heart cells and neurons. They are therefore essential for controlling heart rate and the activity of neural circuits.Roderick MacKinnon received the Nobel Prize in Chemistry in 2003 for his work on ion channels (see “Wonders of the Salt Gate” 1/17/02, also 3/12/02, 5/29/02, 5/01/03). This paper contributes to the “long-awaited crystal structure of the mammalian GIRK2 channel in complex with two subunits of a G protein (a dimer of the Gβ and Gγ subunits), providing information about their mechanism of opening,” Reuveny said. Ion channels such as GIRK2 literally “pump” ions against the direction of osmosis in order to set up the voltage necessary for electrical transmission.It’s nice to see MacKinnon still at work uncovering the secrets of these cellular gates a decade after receiving his Nobel. In the past 10 years, has he seen the light of the Darwinists? Has he found evolution essential to explain how these exquisite molecular gates work? Nope. Neither MacKinnon or Reuveny even mentioned it.Thinking about the action of these gates in slow-motion is amazing enough. Realize, though, that they act lightning-fast, allowing your heart rate to adjust and allowing chemicals and ions to speed through the brain at the speed of thought. Just like in 2002, this is phenomenal evidence for intelligent design.
fruzsina eordogh A Comprehensive Guide to a Content Audit When Gawker reporter Adrian Chen publicly outed troll and influential Reddit user Violentacrez as Michael Brutsch two weeks ago in what many are calling the “best story of the Web,” he changed the nature of the Internet forever. The resulting journalist-sanctioned public shaming:1. Highlighted how ignorant the media is of Internet culture.2. Forced the Internet’s core psyche, sometimes referred to as the “hive mind,” to mature from a teenage boy to a relatively respectful young adult almost overnight.3. Legitimized digital lynch mobs. The Seduction Of A Public ShamingOur technology may have evolved, but our attitudes have not: Nothing pleases humanity more than a good public shaming. Instead of pelting rotten tomatoes at a man locked in the town square stockade, society’s “sinners” are now paraded on national television, courtesy of Anderson Cooper, and branded with a scarlet “T.” (Just Google “Michael Brutsch” if you don’t know what I mean.)Brutsch is now the physical face of the most hated thing on the Internet: the Troll. That anonymous person who goes out of his way to provoke a response. While few people understand what trolls actually are, where they came from and why they do what they do, it is generally accepted that they are the scum of the Web. Hating on them unconditionally is not just acceptable, it’s encouraged, as Cooper implied by calling Brutsch a sad “little person,” sitting “alone in his room, typing on his keyboard, interacting with people he doesn’t even know.” Cooper did stop short of calling him a “neckbeard,” but other outlets have not – he’s been called a “monster,” and even falsely tied to the suicide of Amanda Todd and the “capper” community. Brutsch didn’t create the act of trolling, nor was he the original or most notorious troll. (Brutsch might not even be a troll, as tech culture journalist Xeni Jardin pointed out.) Nor is Brutsch the first man to have an offensive porn collection, or the first man to sexualize children. Regardless, Brutsch will be made an example of, dammit, because we the media (or as Forbes Kashmir Hill called it, “The Internet Cool Kids”) are sick and tired of these vile human beings mucking up our Internet! Never mind that the same media leverages these same transgressors to drive pageviews – all cloaked in hand-wringing and faux outrage (an act Reddit itself is guilty of) . And, of course, the same said media also sexualizes children. Guide to Performing Bulk Email Verification Related Posts Tags:#Trolls The Dos and Don’ts of Brand Awareness Videos Trolls Are Easy TargetsCalling Brutsch’s transgressions “vile” isn’t an overstatement – his stuff was downright disgusting. Brutsch had his hands in some of the most controversial subreddits, including /r/incest, /r/misogyny, /r/beatingwomen, /r/chokeabitch, /r/Jewmerica, /r/Jailbait, /r/niggerjailbait, /r/rapebait, /r/picsofdeadkids and /r/creepshots, just to name a few. If you are offended by those titles, that’s the point of a Troll: Brutsch’s online behavior is so offensive that anyone that wants to be considered a respectable member of society has no choice but to oppose his behavior.As Chen describes trolling in his unmasking piece: “A troll exploits social dynamics like computer hackers exploit security loopholes, and Violentacrez calmly exploited the Reddit hive mind’s powerful outrage machine and free speech values at the same time.” If “troll” wasn’t the hot button word of the year, we’d be calling Brutsch’s digital binders of scantily clad or beaten women “performance art.”Whitney Phillips, a scholar studying Internet trolling culture, put it another way, calling trolls “cultural scavengers” that “engage in a process I describe as cultural digestion: They take in, regurgitate, and subsequently weaponize existing tropes and cultural sensitivities.” Trolls don’t engage in this sort of behavior alone or in a vacuum, Phillips said. Rather, they come out to play when they have a supportive “host culture.” AKA: Reddit.Enabling Adolescent BehaviorThis is exactly what Brutsch meant when he told CNN’s Drew Griffin that Reddit “enabled” and “encouraged” his online behavior: “When two years ago, when all of this was at its height, the audience was appreciative, and supportive of the sort of gallows humor that I put out there.” When Brutsch, who is one year shy of 50, said he was catering to an audience of college kids, he means this both literally and figuratively. Brutsch’s fanbase isn’t necessarily college-aged, but the core Internet psyche is.Established sometime between late 1993 and 1999 through sites like Usenet and WebCrawler, and then reborn in 2003 with the creation of 4chan, the Internet psyche is skeptical, self-absorbed, sadistic and lazy – except when it comes to porn, cute animals, digital pranks and acts of Internet vigilantism. For various reasons, perhaps elated to being wealthy, white and privileged, users connected to this hive mind regularly post the most disturbing (re: misogynist, racist) content they can find. You might see this behavior as a way to compensate for, and feel alive in, their mundane real-world existences. The infamous Usenet troll Ted Frank told Stryker in an interview for his book Epic Win For Anonymous: How 4chan’s Army Conquered The Web, that trolling served as “an educational tool for newcomers.” Modern trolling culture has evolved from its roots on Usenet, however, and Frank “insists” the trolling similarities between 4chan and Usenet are “an etymological coincidence.” (In fact, the notion of trolling can be traced back even further than Usenet: Stryker describes comedian Andy Kaufman as one of the finest examples of a “pre-Internet troll,” and draws parallels with the “Greek prankster Pan, the Norse god Loki, and the conniving Native American Coyote.”)As the Internet goes mainstream and effectively kills the mantra “there are no girls on the Internet,” older generations, women and traditional media increasingly bump into this hive mind. Their presence will age and mature the digitial pysche just by being there, is the hope. Facebook is Becoming Less Personal and More Pro… The 4Chan ConnectionMuch of Reddit’s young, trolling psyche comes from 4chan, specifically /b/, but 4chan has managed to stay out of headlines during this flame war. “I don’t understand why everyone was upset at jailbait, while 4chan continually posts bullshit across the internet and no one bats an eye,” wrote redditor he_cried_out_WTF in response to the Violentacrez controversy. “4chan is apparently the petulant child that everyone pretends doesn’t exist as it throws yet another vase on the floor.”Reddit (and 4chan) aren’t the only social news sites that regularly tap into the vase-throwing Internet psyche: Digg, 9gag, Fark, Something Awful, Encyclopedia Dramatica, Buzzfeed, The Daily Dot, Know Your Meme and the entire I Can Haz Cheezburger clan regularly regularly tune in. Even Erik Martin and fellow paid Reddit employees were guilty of listening to this psyche when they cried “free speech” and “privacy” as knee-jerk reactions, when they could have denounced the misogynistic and racist behavior Brutsch catered to. Brutsch gave the community exactly what it wanted. In return, he heaped up “meaningless Internet points… It had a reward, like the monkey that pushes the button to get a food pellet, it’s addictive” said Brutsch on national television. “Why do people spend money playing [World of Warcraft], why do people play games like that to build up their meaningless stats?, [it’s] exactly the same as 800,000 karma on Reddit.” Gamification, baby.Where Do The Rest Of Us Fit In?Our reaction, as both journalists and “respectable members of society” prove we’re not that different from Brutsch and the dark side of the Internet. We behaved trollishly when we celebrated his job loss, demanded he be imprisoned or burn in hell, and gleefully discussed how his life is now ruined forever. Our collective outrage – what trolls eat for breakfast – also earned us meaningless Internet points in the form of Facebook likes and Twitter RTs. Chen’s piece made White Knights of us all, but is that enough to fix all the societal ills Brutsch was pointing out with his “trolling?” And is a digital lynching really the way to go? We don’t accept this kind of treatment of criminals in the real world – our current justice system is not ruled by a mob mentality – but Chen’s piece and the resulting digital lynching is generally viewed as an acceptable means of punishment online. Perhaps, though, the most ironic aspect of this journalist-sanctioned public trial and execution, is that it generated from well-known Reddit “trolls” themselves.
Kusheshwar Bhagat, 48, has been running a ‘pav bhaji’ stall off Jharsa Road in Part-II of Sector 15 here for more than a decade now. But don’t mistake him for an ordinary street food vendor by the roadside.One of the seven Independent contestants in the fray for the Lok Sabha election in Gurugram, Mr. Bhagat is contesting for the third consecutive time from this parliamentary constituency. He fought two Vidhan Sabha elections earlier. But could never save his deposit.Voters disillusioned“I polled 7,821 votes in 2014 LS election, the highest so far in the four elections,” says Mr. Bhagat, who has moveable assets of around ₹2.5 lakh, besides a Nano car and a house in Delhi. “The voters seem disillusioned with all parties this time. I hope to get around 3 lakh votes… they will vote me to power one day,” says Mr. Bhagat, contesting on the plank of health and education to all.Like him, affordable health and education, development, agrarian crisis, corruption and unemployment are high on the agenda of the Independent candidates in Gurugram. Pawan Kumar, 34, a resident of Gurugram, says he decided to fight the election to raise his voice against lack of jobs and the plight of government schools. “The local youth are not getting employed in the industries in the area. The government schools are in a pitiable condition. Farmers are in distress and the soldiers are dying,” says Mr. Pawan, a graduate, claiming the support of a dozen villages. He says his election symbol, a bucket, will help him strike an instant chord with the voters. He hopes to win with a margin of around one lakh votes.A mini-worldBikaner’s Virender, who claims to have contested five Rajasthan Assembly elections, says that Gurugram is a mini-world with people having come and settled from across the globe. He wants to make it a truly “Millennium City”.Sudesh Kumar of Pataudi, a Scheduled Caste, took the plunge to prepare for the Assembly election later this year. Self-employed, Mr. Sudesh says this Lok Sabha election is a “mock test” for him as he wants to acquaint himself with the election process.Most of these Independent candidates, coming from humble backgrounds, are contesting on shoestring budgets with little money to spare for the canvassing. Mr. Pawan says he is yet to get his campaign material printed and has sought financial support from his father and relatives. He carries his visiting card along and distributes it during his door-to-door campaign.Mr. Bhagat says he spent around ₹15,000 on his campaign in the previous election, but this time he is pinning his hopes on the free publicity through the media. “Every day an article is carried on me in the newspapers. It is enough publicity.I need not spend much on the campaign this time.” says Kusheshwar.Mr. Virender says that he will reach the voters through door-to-door campaign, distributing handbills and send text messages. Mr. Sudesh is active on all popular social media platforms, including Instagram and Facebook, and updates all his canvassing pictures online for the maximum reach.
View comments Read Next “It’s definitely a good partnership as they committed long term in supporting Alab Pilipinas as San Miguel believes in our vision,” the approachable executive said.“They don’t want to disappoint the Filipino fans here and all over the world.”FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSLillard, Anthony lead Blazers over ThunderSPORTSMalditas save PH from shutoutThis isn’t the first go-round for San Miguel in the ABL as it competed for two seasons under the Beermen banner and flaunted the likes of former PBA Most Valuable Players Asi Taulava and Eric Menk, as well as an upstart June Mar Fajardo, who is the reigning four-time PBA MVP.Under coach Leo Austria, San Miguel made two Finals appearances and won the 2013 ABL Championship. Reigning ABL Local MVP Bobby Ray Parks Jr.’s father, the late Bobby Parks, was also a San Miguel import during the late 1980s and previously served as the ABL team’s first head coach. Brace for potentially devastating typhoon approaching PH – NDRRMC Alab parted ways with former backer Tanduay following reported differences between the rhum company’s management and head coach Jimmy Alapag.Curiously, no Tanduay official was present in the team’s 94-91 overtime win against Chong Son Kung Fu on Wednesday.Alab Pilipinas sits at fourth in the 2018 ASEAN Basketball League with its 7-4 card and will unveil its new name when it returns to action on Sunday against the Singapore Slingers.The transition won’t be much of a problem given a number of players’ familiarity with San Miguel Corporation.Veterans Dondon Hontiveros, Rico Maierhofer, and Josh Urbiztondo all saw action for SMC teams in the PBA, while World imports Renaldo Balkman (San Miguel) and Justin Brownlee (Ginebra) have also previously served as reinforcements in the company’s PBA teams.ADVERTISEMENT MOST READ LATEST STORIES Typhoon Kammuri accelerates, gains strength en route to PH Photo by Tristan Tamayo/ INQUIRER.netAlab Pilipinas has forged a new partnership with a familiar face in the ASEAN Basketball League.Team owner Charlie Dy announced that the Philippine side will now be backed by San Miguel, marking the conglomerate’s return to the regional league.ADVERTISEMENT NCAA volleyball: Benilde stops Mapua to boost Final Four chances Don’t miss out on the latest news and information. John Lloyd Cruz a dashing guest at Vhong Navarro’s wedding NEXT BLOCK ASIA 2.0 introduces GURUS AWARDS to recognize and reward industry influencers Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles00:50Trending Articles01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City Slow and steady hope for near-extinct Bangladesh tortoises AFP official booed out of forum Globe Business launches leading cloud-enabled and hardware-agnostic conferencing platform in PH 2 ‘newbie’ drug pushers fall in Lucena sting